abstract：OBJECTIVE:The aim of this study was to investigate the changes in early and late washout rates of 99mTc-methoxyisobutylisonitrile (MIBI) in hypertrophic cardiomyopathy (HCM), and to analyze the relationships between early and late washout rates and the hypertrophic thickness of left ventricular (LV) wall. METHODS:The ...

journal_title：Nuclear medicine communications

authors： Sun M,Li Y,Li N,Liu H,Yin Y,Li D

更新日期：2008-08-01 00:00:00

abstract：BACKGROUND:Coronary artery disease is a leading cause of morbidity and mortality. Multiple imaging modalities are used to screen for significant coronary artery disease. We report the concordance between coronary computed tomography angiography (CTA) and stress cardiac positron emission tomography (CPET) to detect sign...

journal_title：Nuclear medicine communications

authors： Adams GL,Trimble MA,Brosnan RB,Russo CA,Rusband D,Honeycutt EF,Shaw LK,Hurwitz LM,Turkington TG,Hanson MW,Pagnanelli RA,Borges-Neto S

更新日期：2008-07-01 00:00:00

abstract：AIM:The first pathogenetic step in multiple myeloma is the emergence of a limited number of clonal plasma cells, clinically known as monoclonal gammopathy of undetermined significance (MGUS). Patients with MGUS do not have symptoms or end-organ damage but they do have a 1% annual risk of progression to multiple myeloma...

journal_title：Nuclear medicine communications

authors： Giovanella L,Taborelli M,Ceriani L,Zucca E,Cavalli F,Delaloye AB

更新日期：2008-06-01 00:00:00

abstract：BACKGROUND AND AIM:Researchers find that monitoring the differentiation of implanted cells in vivo is difficult. This study was designed to show that it is possible to track the efficacy of transplanted human retinal pigment epithelial cells (RPE cells) in a rat model of Parkinson's disease by using positron emission t...

journal_title：Nuclear medicine communications

authors： Wang R,Zhang J,Guo Z,Shen L,Shang A,Chen Y,Yao S,He T,Yin D,Tian J

更新日期：2008-05-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:The widely applied F-FDG is known for its disadvantage in brain tumour PET imaging because of its high background uptake. C-choline can achieve high contrast of brain tumour imaging and was expected to have higher sensitivity and specificity. We analysed the misdiagnoses in C-choline PET imagin...

journal_title：Nuclear medicine communications

authors： Huang Z,Zuo C,Guan Y,Zhang Z,Liu P,Xue F,Lin X

更新日期：2008-04-01 00:00:00

abstract：OBJECTIVE:Cardiac syndrome X defines patients with typical angina, a positive exercise ECG stress test and angiographically documented normal coronary arteries. In previous studies, post-stress prolonged left ventricular dysfunction (PLVD) using gated SPECT (G-SPECT) had been well correlated with myocardial perfusion a...

journal_title：Nuclear medicine communications

authors： Demir H,Kahraman G,Isgoren S,Tan YZ,Kilic T,Berk F

更新日期：2008-03-01 00:00:00

abstract：OBJECTIVE:We estimated the absorbed doses for (111)In-DTPA-D-Phe(1)-octreotide and (90)Y-DOTA-D-Phe(1)-Tyr(3)-octreotide in the same patients in order to compare the potential effectiveness (tumour dose) and safety (kidney and red marrow dose) of these drugs for peptide-targeted radiotherapy of somatostatin receptor po...

journal_title：Nuclear medicine communications

authors： Barone R,Walrand S,Konijnenberg M,Valkema R,Kvols LK,Krenning EP,Pauwels S,Jamar F

更新日期：2008-03-01 00:00:00

abstract：:Mobile PET/CT or mobile stand alone PET, is becoming more widely available throughout the developed world, allowing many small and medium-sized hospitals that do not have the scale or financial resources to purchase the static diagnostic equipment, to benefit from this imaging technology. Before embarking on such a se...

journal_title：Nuclear medicine communications

authors： Chua SC,Perkins AC,Pearson D,Ganatra RH

更新日期：2008-02-01 00:00:00

abstract：BACKGROUND:Single photon emission tomography (SPECT) of the lung is a well-established non-invasive technique for quantitative assessment of regional lung ventilation and perfusion distribution in children and in adults. However, its application in neonates as well as infants has been scarce because of several practica...

journal_title：Nuclear medicine communications

authors： Sánchez-Crespo A,Rohdin M,Carlsson C,Bergström SE,Larsson SA,Jacobsson H,Lindahl S,Jonsson B

更新日期：2008-02-01 00:00:00

abstract：BACKGROUND:Congenital obstructive renal disease often requires a decision early in the child's life on whether or not surgery is required. Differential renal function (DRF) calculated from the renogram provides important information for the correct decision in this process. A recent publication cast doubt as to the rel...

journal_title：Nuclear medicine communications

authors： Dissing TH,Eskild-Jensen A,Pedersen M,Anderson PJ,Rittig N,Frøkiaer J,Gordon I

更新日期：2008-01-01 00:00:00

abstract：BACKGROUND:In studies of the distribution of lung function, the image quality of lung single photon emission computed tomography (SPECT) is important and one factor influencing it is the reconstruction algorithm. AIM:To systematically evaluate ordered subsets expectation maximization (OSEM) and compare it with filtere...

journal_title：Nuclear medicine communications

authors： Norberg P,Bake B,Jacobsson L,Carlsson GA,Gustafsson A

更新日期：2007-12-01 00:00:00

abstract：OBJECTIVE:To analyse the kinetic changes of uptake, washout and retention of Tc-sestamibi in order to evaluate the protective effects and possible mechanism of ischaemic preconditioning and adenosine preconditioning on myocardium injured by ischaemia/reperfusion. METHODS:Isolated ischaemia/reperfusion rabbit heart mod...

journal_title：Nuclear medicine communications

authors： Liang J,Chen HL,Zhou Y,Xie M,Xu LM,Lin G

更新日期：2007-11-01 00:00:00

abstract：OBJECTIVE:To measure and describe patterns of interobserver variation in visual interpretation of 18-FDG PET in malignant lymphoma. METHODS:Eleven nuclear medicine physicians with different levels of PET experience independently reviewed 37 18F-FDG PET scans of lymphoma patients (10 obtained at presentation, 27 during...

journal_title：Nuclear medicine communications

authors： Zijlstra JM,Comans EF,van Lingen A,Hoekstra OS,Gundy CM,Willem Coebergh J,Bongers V

更新日期：2007-10-01 00:00:00

abstract：PURPOSE:Exclusive use of the half-time of clearance of a filtration marker in the bolus injection, single compartment technique for measuring glomerular filtration rate (GFR) is a convenient approach that gives GFR (GFR(SO)) already scaled for extracellular fluid volume (ECV). It has been criticized as less accurate th...

journal_title：Nuclear medicine communications

authors： Bird NJ,Peters C,Michell AR,Peters AM

更新日期：2007-09-01 00:00:00

abstract：AIMS:To (a) assess the accuracy of 18F-FDG PET/CT in distinguishing malignant from benign pelvic lesions, compared to transvaginal ultrasonography (TVUS) and (b) to establish the role of whole-body 18F-FDG PET/CT, compared to contrast enhanced computed tomography (CT), in staging patients with ovarian cancer. PATIENTS...

journal_title：Nuclear medicine communications

authors： Castellucci P,Perrone AM,Picchio M,Ghi T,Farsad M,Nanni C,Messa C,Meriggiola MC,Pelusi G,Al-Nahhas A,Rubello D,Fazio F,Fanti S

更新日期：2007-08-01 00:00:00

abstract：OBJECTIVE:To verify the negative predictive value of pulmonary ventilation/perfusion scintigraphy with single photon emission computed tomography (V/Q SPECT) in ruling out pulmonary thromboembolism. METHODS:V/Q SPECT using 99mTc-Technegas was performed on 584 patients to rule out pulmonary thromboembolism between Octo...

journal_title：Nuclear medicine communications

authors： Leblanc M,Leveillée F,Turcotte E

更新日期：2007-08-01 00:00:00

abstract：:The suggestion by the National Institute for Clinical Excellence (NICE) to more than triple the number of myocardial perfusion scintigraphy (MPS) procedures carried out by the NHS each year is a challenge both in terms of numbers of gamma cameras available to carry out the scans and qualified staff to supervise stress...

journal_title：Nuclear medicine communications

authors： Jones I,Latus K,Bartle L,Gardner M,Parkin V,Guideline Development and Writing Group, British Nuclear Medicine Society and British Nuclear Cardiac Society.

更新日期：2007-07-01 00:00:00

abstract：OBJECTIVES:The determination of lesion boundaries on FDG PET is difficult due to the point-spread blurring and unknown uptake of activity within a lesion. Standard threshold-based methods for volumetric quantification on PET usually neglect any size dependence and are biased by dependence on the signal-to-background ra...

journal_title：Nuclear medicine communications

authors： van Dalen JA,Hoffmann AL,Dicken V,Vogel WV,Wiering B,Ruers TJ,Karssemeijer N,Oyen WJ

更新日期：2007-06-01 00:00:00

abstract：PURPOSE:Increasing evidence, primarily from animal studies and patients with compromised neurotransmitter systems, indicates a possibly important role for dopamine in modulating sleep. We therefore conducted this study to explore the relation between sleep and dopamine in healthy adults. METHODS:We used the Pittsburgh...

journal_title：Nuclear medicine communications

authors： Lee BF,Chiu NT,Kuang Yang Y,Lin Chu C

更新日期：2007-05-01 00:00:00

abstract：PURPOSE:To investigate the accuracy of different interpretative approaches and to evaluate the management implications of fluorodeoxyglucose positron emission tomography/computed tomography (FDG PET/CT) in cutaneous malignant melanoma. METHODS:We retrospectively identified 60 consecutive patients who underwent 76 PET/...

journal_title：Nuclear medicine communications

authors： Falk MS,Truitt AK,Coakley FV,Kashani-Sabet M,Hawkins RA,Franc B

更新日期：2007-04-01 00:00:00

abstract：OBJECTIVE:This study investigated dopamine transporter blockade in the rat striatum after treatment with various doses of methylphenidate using a high-resolution small animal SPECT ('TierSPECT') and I-FP-CIT. METHODS:I-FP-CIT was administered intravenously 1 h after intraperitoneal injection of methylphenidate (3 mg.k...

journal_title：Nuclear medicine communications

authors： Nikolaus S,Antke C,Beu M,Kley K,Larisch R,Wirrwar A,Müller HW

更新日期：2007-03-01 00:00:00

abstract：OBJECTIVE:To evaluate the potential of (99m)Tc-pamidronate ((99m)Tc-APD) against (99m)Tc-medronate ((99m)Tc-MDP) as a new bone-seeking agent using intact bone and fractured femur in a rat model. METHODS:(99m)Tc-APD was prepared by the stannous reduction method. Scintigraphic images were obtained at 2 h and 24 h after ...

journal_title：Nuclear medicine communications

authors： Kumar V,Kumar D,Howman-Giles RB,Little DG

更新日期：2007-02-01 00:00:00

abstract：BACKGROUND:The purpose of this study was to evaluate the uptake of (99m)Tc-NC100668 into blood clots and elucidate the potential for medications commonly used to treat thromboembolism to interfere with the uptake and retention of (99m)Tc-NC100668. METHODS:(99m)Tc-NC100668 in vivo uptake and retention in a range of blo...

journal_title：Nuclear medicine communications

authors： Edwards D,Lewis J,Battle M,Lear R,Farrar G,Jon Barnett D,Godden V,Oliveira A,Coombes C,Ahlström H

更新日期：2007-01-01 00:00:00

abstract：OBJECTIVES:Myocardial perfusion SPECT is frequently affected by artefacts related to abdominal activity. Metoclopramide has been suggested to relieve this, but two previous studies have shown conflicting results. METHODS:Ninety-five patients received 10 mg metoclopramide orally after injection of 99mTc-tetrofosmin for...

journal_title：Nuclear medicine communications

authors： Grüning T,Brogsitter C,Khonsari M,Jones IW,Nevin SM,Burchert W

更新日期：2006-12-01 00:00:00

abstract：OBJECTIVES:The aim of this study was to evaluate the usefulness of (123)I-iomazenil (IMZ) single photon emission computed tomography (SPECT) for the pre-surgical identification of epileptogenic areas in patients with temporal lobe epilepsy and to compare the results with those of (123)I-IMP SPECT and (18)Fluorodeoxyglu...

journal_title：Nuclear medicine communications

authors： Kaneko K,Sasaki M,Morioka T,Koga H,Abe K,Sawamoto H,Ohya N,Yoshiura T,Mihara F,Honda H

更新日期：2006-11-01 00:00:00

abstract：BACKGROUND:The indication for sentinel node biopsy (SNB) has not been fully established yet for patients with ductal carcinoma in situ (DCIS). AIM:To relate the conversion rate to invasive carcinoma with sentinel node positivity in high risk DCIS, and to refine the clinical presentation analysis in order to better sel...

journal_title：Nuclear medicine communications

authors： Fraile M,Gubern JM,Rull M,Julián FJ,Serra C,Llatjós M,Culell P,Puig P,Solà M,Vallejos V,Mariscal A,Janer J,Deulofeu P,Fusté F

更新日期：2006-10-01 00:00:00

abstract：:Foot problems are common causes of disability in diabetic patients with as many as 25% expected to develop severe foot or leg problems during their lifetimes. Although skin ulceration is the most frequent problem, bones may also be involved in two different clinical conditions: osteomyelitis and Charcot osteoarthropat...

journal_title：Nuclear medicine communications

authors： Giurato L,Uccioli L

更新日期：2006-09-01 00:00:00

abstract：BACKGROUND:Early experience demonstrated absorbed dose in radiation synovectomy is about 100 Gy. For reaching this dose, the applied radioactivity should be calculated. METHOD:Twenty-nine synovitic models of rabbit were treated by intra-articular injection of [(188)Re]rhenium sulfide and histological changes of synovi...

journal_title：Nuclear medicine communications

authors： Li P,Yu J,Chen G,Jiang X,Tang Z,Chen S,Jiang L,Tang L,Yin D

更新日期：2006-08-01 00:00:00

abstract：BACKGROUND:Scintimammography using (99m)Tc-labelled isonitriles, sestamibi and tetrofosmin, has become a mature technique in the adjunctive setting for the diagnosis of primary breast cancer. To establish an evidence base for its use, clinically, a meta-analysis was performed on both single-site and multi-centre trials...

journal_title：Nuclear medicine communications

authors： Hussain R,Buscombe JR

更新日期：2006-07-01 00:00:00

abstract：AIM:This study was undertaken to evaluate different methods for the detection of small changes in uptake between single-photon emission computed tomography (SPECT) examinations in the same individual. No standard exists for making digital evaluations at single-photon examinations. For this purpose, we employed a patien...

journal_title：Nuclear medicine communications

authors： Jacobsson H,Wilczek B,Bergh J,von Schoultz E,Eriksson E,Larsson SA

更新日期：2006-04-01 00:00:00

abstract：:The term 'fever of unknown origin' includes a wide range of conditions that often remain undiagnosed. The possibility of an infection must be promptly diagnosed in order to begin appropriate therapy. Imaging with radiopharmaceuticals, computed tomography, magnetic resonance imaging and ultrasound are the most commonly...

journal_title：Nuclear medicine communications

authors： Cascini GL,De Palma D,Matteucci F,Biggi A,Rambaldi PF,Signore A,Mansi L

更新日期：2006-03-01 00:00:00

abstract：BACKGROUND:Follow-up of 131I whole-body scanning after 131I ablation is associated with potential stunning. Previous studies have suggested that, for scanning, 123I is more sensitive than 131I in identifying thyroid tissue, but its specificity when positive is less certain. AIM:The use of 123I as an imaging agent in p...

journal_title：Nuclear medicine communications

authors： Ali N,Sebastian C,Foley RR,Murray I,Canizales AL,Jenkins PJ,Drake WM,Plowman PN,Besser GM,Chew SL,Grossman AB,Monson JP,Britton KE

更新日期：2006-02-01 00:00:00

abstract：OBJECTIVE:The herpes simplex virus thymidine kinase (HSVtk) gene has frequently been applied as a reporter gene for monitoring transgene expression in animal models. In clinical gene therapy protocols, however, extremely low expression levels of the transferred gene are generally observed. Consequently, sensitive and s...

journal_title：Nuclear medicine communications

authors： Buursma AR,Rutgers V,Hospers GA,Mulder NH,Vaalburg W,de Vries EF

更新日期：2006-01-01 00:00:00

abstract：AIM:To evaluate the biodistribution, internal radiation dosimetry and toxicity of the humanized MAb h-R3 labelled with Tc in humans. METHODS:Twenty-five patients with suspected epithelial-derived tumours were included in this study and divided into two groups: group I consisted of 10 patients who received 3 mg/1110 MB...

journal_title：Nuclear medicine communications

authors： Torres LA,Perera A,Batista JF,Hernández A,Crombet T,Ramos M,Neninger E,Pérez M,Sánchez EL,Romero S,Aguilar V,Coca MA,Iznaga-Escobar N

更新日期：2005-12-01 00:00:00

abstract：AIM:99mTc-HL91 is a new hypoxia agent and can identify acutely ischaemic viable myocardium in a canine model using a standard gamma camera. The purpose of the study was to determine whether this tracer could be used to detect regional ischaemia in chronic ischaemic myocardium in a swine model. METHOD:Using a porcine m...

journal_title：Nuclear medicine communications

authors： Wu YW,Lee CM,Huang YH,Chou NK,Yen RF,Tzen KY,Huang PJ

更新日期：2005-12-01 00:00:00

abstract：OBJECTIVES:This survey was designed to assess the trends in the frequencies of nuclear medicine procedures in the UK and to determine their contributions to the annual collective effective dose to the UK population. The average activities administered by nuclear medicine departments were compared with guidance on diagn...

journal_title：Nuclear medicine communications

authors： Hart D,Wall BF

更新日期：2005-11-01 00:00:00

abstract：OBJECTIVE:Two ligands viz. tert-butyl dithiocarbamate (TBDTC) and methoxyisobutyl dithiocarbamate (MIBDTC), which are analogous to the tert-butyl isonitrile (TBI) and sestamibi (MIBI) ligands, were synthesized and labelled with the [99mTcN] core to evaluate their potential as myocardial agents. As these complexes have ...

journal_title：Nuclear medicine communications

authors： Mathur A,Mallia MB,Subramanian S,Banerjee S,Kothari K,Dhotare B,Sarma HD,Venkatesh M

更新日期：2005-11-01 00:00:00

abstract：OBJECTIVE:In-vivo quantitative cerebral blood flow (CBF) measurement using positron emission tomography (PET) has typically employed invasive arterial blood sampling procedure to determine the arterial input function (AIF). The present study was performed to provide a non-invasive quantitative CBF measurement technique...

journal_title：Nuclear medicine communications

authors： Yee SH,Jerabek PA,Fox PT

更新日期：2005-10-01 00:00:00

abstract：AIM:It has been reported that dyslipidaemia impairs left ventricular systolic (LVs) and diastolic (LVd) functions, irrespective of atherogenic effects, in the setting of coronary artery disease. The aim of the present study was to evaluate the effects of anti-lipidaemic therapy on LVs and LVd functions by means of mult...

journal_title：Nuclear medicine communications

authors： Entok E,Unalir A,Cavusoglu Y,Timuralp B,Vardareli E

更新日期：2005-09-01 00:00:00

abstract：BACKGROUND:Lymph node metastases are significant prognostic factors in localized non-small-cell lung cancer (NSCLC). Nodal micrometastases may not be detected using current histological methods. AIM:To determine the accuracy and role of sentinel lymph nodes (SLNs) in patients with NSCLC. METHODS:Intraoperative techne...

journal_title：Nuclear medicine communications

authors： Atinkaya C,Ozlem Küçük N,Koparal H,Aras G,Sak SD,Ozdemir N

更新日期：2005-08-01 00:00:00